Tuesday, February 25, 2025

What is sentinel node biopsy?

A sentinel node biopsy is a surgical procedure used to determine if cancer has spread beyond a primary tumor into the lymphatic system. Here's a breakdown of key information:
What it is:
 * It involves identifying and removing the "sentinel lymph node," which is the first lymph node to which cancer cells are most likely to spread.
 * This node is considered the "gateway" to the rest of the lymph node system.
 * If the sentinel node is cancer-free, it's highly likely that the cancer hasn't spread to other lymph nodes.
How it's done:
 * A radioactive substance and/or a blue dye is injected near the tumor.
 * These tracers travel through the lymphatic system to the sentinel node, making it visible.
 * The surgeon locates and removes the sentinel node(s).
 * The removed tissue is examined under a microscope for cancer cells.
Why it's done:
 * To determine the stage of cancer.
 * To guide treatment decisions.
 * It can help avoid the removal of many lymph nodes (lymphadenectomy) if cancer has not spread, which can reduce the risk of complications like lymphedema.
 * It is common practice for cancers such as:
   * Breast cancer
   * Melanoma
Key points:
 * Lymph nodes are part of the immune system and help filter harmful substances.
 * Cancer cells often spread to lymph nodes first.
 * A negative sentinel node biopsy suggests cancer has not spread.
 * A positive sentinel node biopsy may indicate the need for further treatment, such as additional lymph node removal.
I hope this information is helpful.

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